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Breast Cancer and Chemicals Policy Project

The BCCP aims to help close the data gap in chemical hazard information by proposing an approach to chemical testing that accounts for the events in biological pathways associated with increased risk of breast cancer

Executive Summary
BCCP Project Presentation

Funded by the California Breast Cancer Research Program (CBCRP), the Breast Cancer and Chemicals Policy project aims to:

Identify key toxicological methods for detecting chemical contributors to breast cancer,

Investigate testing strategies that will provide the most useful information to policy makers, consumers and businesses attempting to reduce chemical hazards, and

Recommend means for addressing current gaps in toxicological methods and scientific knowledge in order to more effectively manage chemicals.

The year-long project is co-directed by Megan Schwarzman (PI), MD, MPH, Research Scientist at the UC, Berkeley School of Public Health, Center for Occupational and Environmental Health (COEH), and Sarah Janssen, MD, PhD, MPH, Science Fellow at the Natural Resources Defense Council (NRDC). The project’s final report will be published in April, 2010.

 

Pathways to Breast Cancer: A Case Study for Innovation in Chemical Safety Evaluation

Download Full Report

Events:
Project results to be presented in Plenary session at CBCRP Annual Symposium Sept 25th: http://www.cbcrp.org/symposium/

Downloads:
CBCRP Introduction
Policy Background to the Breast Cancer and Chemicals Policy Project
Expert Panel Member List
Panel Member Bios

Presentations:
A California Roadmap for Identifying Chemicals that Affect Breast Cancer Risk Presentations at the AAAS Annual Conference, February 19, 2010
Introduction Sarah Janssen
Chemicals Policy Context Megan Schwarzman Early Life Exposures and Lifelong Impact on the Mammary Gland Suzanne Fenton
Findings of the Breast Cancer and Chemicals Policy Project Lauren Zeise

Background Articles:
Rethinking Breast Cancer Toxicology (C&EN, March 2010) [download pdf]
Identifying Chemicals That Cause Breast Cancer: An International Perspective
Vincent James Cogliano, PhD
REACH Dataset Tests Richard Denison, PhD
Toxicity Testing in the 21st Century: A Vision and a Strategy National Academy of Sciences
Developmental, Cellular, and Molecular Basis of Human Breast Cancer Jose Russo, et al.
Chemicals Causing Mammary Gland Tumors in Animals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention Ruthann A. Rudel, MS et al.
Endocrine-Disrupting Compounds and Mammary Gland Development: Early Exposure and Later Life Consequences Suzanne E. Fenton, et al.
Risk Assessment Primer, Lauren Zeise, PhD


Contact

Breast Cancer and Chemicals Policy Project
Center for Occupational and Environmental Health
School of Public Health, UC Berkeley
50 University Hall #7360
Berkeley, CA 94720

Sarah Janssen, Co-Director, sjanssen@nrdc.org 415-875-6126
Megan Schwarzman, Co-Director and PI, mschwarzman@berkeley.edu 510-643-4685