Chemicals and Breast Cancer Booklet (PDF)

English: Print
Spanish: Print


Can Chemicals Cause Breast Cancer? Factsheets (PDF)

English: Web Print
Spanish: Web Print
Chinese: Web Print
Vietnamese: Web Print


Breast Cancer and Chemicals Policy Project

The BCCP aims to inform the generation of chemical hazard information by developing an approach to chemical testing that accounts for events in biological pathways associated with increased risk of breast cancer.

Executive Summary (PDF)

Funded by the California Breast Cancer Research Program (CBCRP), the goals of the Breast Cancer and Chemicals Policy project were to:

Develop an approach for toxicological testing that would detect chemical contributors to breast cancer risk,

Identify research needs and recommend improvements to existing test methods, and

Pilot a model process that could be applied to other disease endpoints, informing the ultimate aim of producing a comprehensive approach to identifying hazardous chemicals.

The project was co-directed by Principle Investigator Megan Schwarzman, MD, MPH, Research Scientist at the UC Berkeley School of Public Health, Center for Occupational and Environmental Health (COEH), and Sarah Janssen, MD, PhD, MPH, formerly Senior Scientist at the Natural Resources Defense Council (NRDC), now with the UCSF Division of Occupational and Environmental Medicine, and the Kaiser Permanente Medical Center, San Francisco.



Screening for Chemical Contributions to Breast Cancer Risk: A Case Study for Chemical Safety Evaluation - Environmental Health Perspectives

Evaluating Chemical Effects on Mammary Gland Development:A Critical Need in Disease Prevention - Reproductive Toxicology (PDF)


Pathways to Breast Cancer - the Full Report (PDF)

Pathways to Breast Cancer: A Case Study for Innovation in Chemical Safety Evaluation

Download Full Report (PDF)


A California Roadmap for Identifying Chemicals that Affect Breast Cancer Risk
Presentations at the AAAS Annual Conference, February 19, 2010

Introduction (PDF) Sarah Janssen
Chemicals Policy Context (PDF) Megan Schwarzman
Early Life Exposures and Lifelong Impact on the Mammary Gland
(PDF) Suzanne Fenton
Findings of the Breast Cancer and Chemicals Policy Project (PDF) Lauren Zeise

Project Background Materials

Rethinking Breast Cancer Toxicology (C&EN, March 2010)
Identifying Chemicals That Cause Breast Cancer: An International Perspective (PDF)
Vincent James Cogliano, PhD
REACH Dataset Tests (PDF) Richard Denison, PhD
Toxicity Testing in the 21st Century: A Vision and a Strategy (PDF) National Academy of Sciences
Developmental, Cellular, and Molecular Basis of Human Breast Cancer (PDF) Jose Russo, et al.
Chemicals Causing Mammary Gland Tumors in Animals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention (PDF) Ruthann A. Rudel, MS et al.
Endocrine-Disrupting Compounds and Mammary Gland Development: Early Exposure and Later Life Consequences (PDF) Suzanne E. Fenton, et al.
Risk Assessment Primer (PDF) Lauren Zeise, PhD


Breast Cancer and Chemicals Policy Project
Center for Occupational and Environmental Health
School of Public Health, UC Berkeley
50 University Hall #7360
Berkeley, CA 94720

Sarah Janssen, Co-Director,
Megan Schwarzman, Co-Director and PI, 510-643-4685