Courtney Broaddus

Michele La Merrill, PhD

Assistant Professor
Environmental Health Sciences
Department of Environmental Toxicology
University of California
Berkeley , CA 95616
mlamerrill@ucdavis.edu
530-754-7254
http://lamerrill.ucdavis.edu

Current Research Interests
• Perinatal exposures and risk of metabolic syndrome
• Perinatal exposures and risk of breast cancer
• Gene regulation in thermogenesis

Courses
Undergraduate
• ETX 10. Introduction to Environmental Toxicology (3 units)
• ETX 140. Genes & The Environment (3 units)

Graduate
• GGG 201A - Advanced Genetic Analysis (5 units)
• EPI 272 - Cancer Epidemiology (2 units)

Key Publications

  1. Netusil NR, Boyd E, van Giffen Z, and La Merrill MA.  Can open spaces be self-financing: results from Portland, Oregon.Choices2000, Second Quarter, 21-23.
  2. Gordon R, Hunter K, La Merrill M, Sørensen P, Threadgill D, and Pomp D. Genotype x diet interactions in mice predisposed to mammary cancer: II. tumors and metastasis. Mammalian Genome, 2008, 19: 179-189, PMID18288525.
  3. La Merrill M, Baston DS, Denison MS, Birnbaum LS, and Threadgill DW. Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. American Journal of Physiology-Endocrinology and Metabolism, 2009, 296: E203-210, PMID18840765/PMCID:PMC2636987.
  4. La Merrill M, Kuruvilla BS, Birnbaum LS, Pomp D, and Threadgill DW. Dietary fat alters pubertal body composition and P450 induction following maternal TCDD exposure in DBA/2J mice. Environmental Health Perspectives, 2009, 117:1414-1419, PMID19750107/PMCID:PMC2737019.
  5. La Merrill M*, Gordon R, Hunter K, Threadgill D, and Pomp D. Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression. Clinical and Experimental Metastasis2010, 27: 107-116, PMID20151316.
  6. La Merrill M, Harper R, Birnbaum LS, Cardiff RD, and Threadgill DW. Maternal TCDD along with a diet high in fat increases mammary cancer incidence in mice. Environmental Health Perspectives, 2010, 118: 596-601 (Cover article and Science Selection), PMID20435547/PMCID:PMC2866672.
  7. Gordon R, La Merrill M, Hunter K, Threadgill D, and Pomp D. Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis. Clinical and Experimental Metastasis,2010, 27: 279-293, PMID20354763.
  8. La Merrill M*, Stein CR, Landrigan P, Engel SM, and Savitz DA. Prepregnancy body mass index, smoking during pregnancy, and infant birth weight. Annals of Epidemiology2011, 21: 413-420PMID21421328/PMCID:PMC3090467.
  9. La Merrill M*, Torres-Sanchez L, Ruiz-Ramos R, López-Carrillo L, Cebrián Garcia M, and Chen J. The association between first trimester micronutrient intake, MTHFR genotypes, and global DNA methylation in pregnant women.  Journal of Maternal-Fetal and Neonatal Medicine,2012, 25: 133-137, PMID21443409/PMCID:PMC3279137.
  10. La Merrill M*, Cirillo PM, Terry MB, Krigbaum NY, Flom JD, and Cohn BA. Prenatal exposure to the pesticide DDT and hypertension diagnosed in women before age 50: a longitudinal birth cohort study. Environmental Health Perspectives,2013, 121: 594-599, PMID 23591545/PMCID:PMC3673196.
  11. La Merrill M*,Karey E, Moshier E, Lindtner C, La Frano MR, Newman JW, Buettner C. Perinatal exposure of mice to the pesticide DDT impairs energy expenditure and metabolism in adult female offspring. PLOS ONE, 2014, 9: e103337, PMCID: PMC4116186.
  12. La Merrill MA*, Cirillo PM, Krigbaum NY, and Cohn BA. The impact of prenatal parental tobacco smoking on risk of diabetes mellitus in middle-aged women. Journal of Developmental Origins of Health and Disease, 2015, Feb 10:1-8, PMID25665487.
  13. Cohn BA, La Merrill M, Krigbaum NY, Yeh G, Park JS, Zimmermann L, Cirillo PM. DDT exposure in utero and breast cancer. Journal of Clinical Endocrinology and Metabolism, 2015, PMID 26079774.
  14. Ishikawa T, Graham JL, Stanhope KL, Havel PJ, La Merrill MA*. Effect of DDT exposure on lipids and energy balance in obese Sprague-Dawley rats before and after weight loss. Toxicology Reports, 2015, PMID processing. Open Access.

Courses
Undergraduate
• ETX 10. Introduction to Environmental Toxicology (3 units)
• ETX 140. Genes & The Environment (3 units)

Graduate
• GGG 201A - Advanced Genetic Analysis (5 units)
• EPI 272 - Cancer Epidemiology (2 units)