University of California
Martyn T. Smith, PhD

Martyn T. Smith, PhD

Professor of Toxicology
School of Public Health
Division of Environmental Health Sciences
University of California
Berkeley, CA 94720-7356
martynts@berkeley.edu
510-642-8770 Fax: 510-642-0427
Superfund Basic Research Program
 
Current Research Interests
• Development and application of biomarkers
• Benzene toxicity
• The causes of leukemia and lymphoma
• Genetic susceptibility to disease
• Children's Environmental Health
 
Key Publications

1. Carlos-Wallace FM, Zhang L, Smith MT, Rader G, Steinmaus C (2016) Parental, In Utero, and Early-Life Exposure to Benzene and the Risk of Childhood Leukemia: A Meta-Analysis.
Am J Epidemiol. Jan 1;183(1):1-14. PMID: 26589707.

2. Smith MT, de la Rosa R, Daniels SI (2015) Using exposomics to assess cumulative risks and promote health. Environ Mol Mutagen.
Dec;56(9):715-23. PMCID: PMC4636923.

3. Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert P, Hecht SS, Bucher JR, Stewart BW, Baan R, Cogliano VJ, Straif K (2015) Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis. Environ Health Perspect. Nov 24. [Epub ahead of print]. PMID: 26600562.

4. Sampson JN, Wheeler WA, Yeager M, Panagiotou O, Wang Z, Berndt SI, Lan Q, …,Smith MT, et al. (2015) Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. J Natl Cancer Inst. Oct 12;107(12). pii: djv279. doi: 10.1093/jnci/djv279. Print 2015 Dec. PMID: 26464424.

5. Steinmaus C, Castriota F, Ferreccio C, Smith AH, Yuan Y, Liaw J, Acevedo J, Pérez L, Meza R, Calcagno S, Uauy R, Smith MT (2015) Obesity and excess weight in early adulthood and high risks of arsenic-related cancer in later life. Environ Res. Oct;142:594-601. PMCID: PMC4664040.

6. Loomis D, Guyton K, Grosse Y, El Ghissasi F, Bouvard V, Benbrahim-Tallaa L, Guha N, Mattock H, Straif K, …, and Smith MT with the International Agency for Research on Cancer Monograph Working Group, IARC, Lyon, France (2015) Carcinogenicity of lindane, DDT, and 2,4-dichlorophenoxyacetic acid. Lancet Oncol. Aug;16(8):891-2. PMID: 26111929.

7. Ji Z, McHale CM, Bersonda J, Tang J, Smith MT, Zhang L (2015) Induction of centrosome amplification by formaldehyde, but not hydroquinone, in human lymphoblastoid TK6 cells. Environ Mol Mutagen. Jul;56(6):535-44. PMID: 25821186.

8. Pearce NE, Blair A, Vineis P, Ahrens W, Andersen A, Anto JM, Armstrong BK, Baccarelli AA, Beland FA, …, Smith MT, et al. (2015) IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Humans. Environ Health Perspect. Jun;123(6):507-14.PMCID: PMC4455595.

9. Landrigan PJ, Wright RO, Cordero JF, Eaton DL, Goldstein BD, Hennig B, Maier RM, Ozonoff DM, Smith MT, Tukey RH (2015) The NIEHS Superfund Research Program: Twenty-Five Years of Translational Research for Public Health. Environ Health Perspect. Oct;123(10)909-18. PMCID: PMC4590764.

10. Shen H, McHale CM, Smith MT, Zhang L (2015) Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9. Mutat Res Rev Mutat Res. Apr-Jun;764:31-42. PMCID: PMC4456615.

11. Seow WJ, Zhang L, Vermeulen R, Tang X, Hu W, Bassig BA, Ji Z, Shiels MS, Kemp TJ, Shen M, Qiu C, Reiss B,Beane Freeman L, Blair A, Kim C, Guo W, Wen C5, Li L, Pinto LA, Huang H, Smith, Hildesheim A, Rothman N,Lan Q (2015) Circulating immune/inflammation markers in Chinese workers occupationally exposed to formaldehyde. Carcinogenesis. Aug;36(8)852-7. PMCID: PMC454853.

12. Wang SS, Vajdic CM, Linet MS, Slager SL, Voutsinas J, Nieters A, de Sanjose S, Cozen W, Alarcón GS, Martinez-Maza O, Brown EE, Bracci PM, Lightfoot T, Turner J, Hjalgrim H, Spinelli JJ, Zheng T, Morton LM, Birmann BM, Flowers CR, Paltiel O, Becker N, Holly EA, Kane E, Weisenburger D, Maynadie M, Cocco P, Foretova L, Staines A, Davis S, Severson R, Cerhan JR, Breen EC, Lan Q, Brooks-Wilson A, De Roos AJ, Smith MT, et al. (2015) Associations of Non-Hodgkin Lymphoma (NHL) Risk With Autoimmune Conditions According to Putative NHL Loci. Am J Epidemiol. Mar 15;181(6):406-21. PMCID: PMC4402340.

13. Zhang L, Samad A, Pombo-de-Oliveira MS, Scelo G, Smith MT, Feusner J, Wiemels JL, Metayer C (2015) Global characteristics of childhood acute promyelocytic leukemia. Blood Rev. Mar;29(2):101-25. PMCID: PMC4379131.

14. Vijai J, Wang Z, Berndt SI, Skibola CF, Slager SL, de Sanjose S, …, Smith MT, et al. (2015) A genome-wide association study of marginal zone lymphoma shows association to the HLA region. Nat Commun. Jan 8;6:5751. PMCID: PMC4287989.

15. Lan Q, Smith MT, Tang X, Guo W, Vermeulen R, Ji Z, Hu W, Hubbard AE, Shen M, McHale CM, Qiu C, Liu S, Reiss B,Beane-Freeman L, Blair A, Ge Y, Xiong J, Li L, Rappaport SM, Huang H, Rothman N, Zhang L (2015) Chromosome-wide aneuploidy study of cultured circulating myeloid progenitor cells from workers occupationally exposed to formaldehyde. Carcinogenesis. Jan;36(1):160-7. PMCID: PMC4291049.

Teaching
• PH 270B Advanced Toxicology (UCB)
• NST 11 Introduction to Toxicology (UCB)
 
Honors
• American Association for the Advancement of Science (AAAS) Fellow